Friday Lecture Series

Ernst A.H. Friedheim Memorial Lecture

Envelope Assembly and Function in Bacterial Pathogens

Olaf Schneewind, M.D., Ph.D.,

Louis Block Professor and chair, department of microbiology,

University of Chicago

November 11,  2011

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Cheng, A. G., M. McAdow, H. K. Kim, T. Bae, D. M. Missiakas, and O. Schneewind. 2010. Contribution of coagulases towards staphylococcus aureus disease and protective immunity. PLoS Pathogens 6, (8): 19-20

Hendrickx, A. P. A., J. M. Budzik, S. -Y Oh, and O. Schneewind. 2011. Architects at the bacterial surface-sortases and the assembly of pili with isopeptide bonds. Nature Reviews Microbiology 9, (3): 166-171

Kern, J., and O. Schneewind. 2010. BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Molecular microbiology 75, (2): 324-332

Kim, H. K., A. G. Cheng, H. -Y Kim, D. M. Missiakas, and O. Schneewind. 2010. Nontoxigenic protein A vaccine for methicillin-resistant staphylococcus aureus infections in mice. Journal of Experimental Medicine 207, (9): 1863-1870

Kim, H. K., A. DeDent, A. G. Cheng, M. McAdow, F. Bagnoli, D. M. Missiakas, and O. Schneewind. 2010. IsdA and IsdB antibodies protect mice against staphylococcus aureus abscess formation and lethal challenge. Vaccine 28, (38): 6382-6392

Schneewind, O., and D. Missiakas. 2011. Structural vaccinology to thwart antigenic variation in microbial pathogens. Proceedings of the National Academy of Sciences of the United States of America 108, (25): 10029-10030

Thammavongsa, V., J. W. Kern, D. M. Missiakas, and O. Schneewind. 2009. Staphylococcus aureus synthesizes adenosine to escape host immune responses. Journal of Experimental Medicine 206, (11): 2417-2427