Project to Map Human Proteins 50% Complete

NEW YORK (GenomeWeb News) – Scientists involved in the Human Protein Atlas are about halfway through their effort to generate and compile data on all known human proteins, members of the team announced recently.

As of mid-November, the group of investigators from Sweden, South Korea, China, and India had reportedly characterized about 10,000 of the 20,000 predicted proteins in the human body. Using genetic data as a guide, the researchers are continuing to put together localization, functional, and other proteomic data for the resource, which they expect to finish in 2015.

The Human Protein Atlas relies on a high-throughput, antibody-based proteomics approach in which genetic sequence information is used to find and develop antibodies against specific protein epitope signature tags.

The project, which is led by researchers at the Royal Institute in Stockholm, Uppsala University, and Lab Surgpath in Mumbai, receives funding from the Knut and Alice Wallenberg Foundation.