Recommended Readings: Konstantin Goulianos Ph.D. May 24 2010

Monday Seminar Series

Rockefeller at the Large Hadron C ollider

Konstantin Goulianos, Ph.D.,


Laboratory of Experimental High Energy Physics

The Rockefeller University

May 24, 2010

3:45 p.m.-5:00 p.m.  Welch Hall Level Two


Recommended Readings:

 The CMS Collaboration. 2010. Measurement of Bose–Einstein Correlations in  proton-proton  Collisions at p s =0.9 and 2.36 TeV at the LHC.  CERN-PH-EP-2010-010 2010/05/19

The CMS Collaboration. 2010. Transverse-momentum and pseudorapidity distributions of  charged hadrons in pp collisions at ps = 7 TeV.  CERN-PH-EP-2010-009 2010/05/19

Chatrchyan, S., et al. incl.  Bhatti, A., Demortier, L., Goulianos,  K., Hatakeyama, K.,  Mesropian, C.   2009  The CMS experiment at the CERN LHC. JOURNAL OF  INSTRUMENTATION    3( S08004).

Merali, Zeenya.  2010.  Physics: The Large Human Collider  Nature 464: 482-484    doi:10.1038/464482a

Brumfield, Geoff.  2009.  LHC sees particles circulate once more Nature News (23 November  2009) doi:10.1038/news.2009.1104

 The CMS Collaboration.  (2010). Transverse-momentum and pseudorapidity distributions of charged hadrons in pp   collisions at root s=0.9 and 2.36 TeV.  JOURNAL OF HIGH ENERGY PHYSICS    issue 2 (041).

Abulencia, A., Adelman, J., Affolder, T., et al.  2007.  Observation of exclusive electron- postitron Production in hadron-handron.   Physical Review Letters   98(11  article number 112001)

Goulianos K .  2005.  Multigap diffraction at LHC . 2005.  Conference Information: 13th  International Workshop on Deep Inelastic Scattering (DIS 2005), APR 27-MAY 01,  2005 Madison, WI.  Deep Inelastic Scattering.   AIP CONFERENCE  PROCEEDINGS   792: 515-518

Recommended Readings: Hermann Steller Ph.D. June 7 2010

Monday Seminar Series

Regulation of Apoptosis by the Ubiquitin-Proteasome System

Hermann Steller, Ph.D.,


Strang Professor; Investigator, HHMI
Strang Laboratory of Apoptosis and Cancer Biology

 June 7, 2010

3:45 p.m.-5:00 p.m.  Welch Hall Level Two

Recommended Readings:

Cecarini V, Quassinti L, Di Blasio A, et al.  2010. Effects of thymoquinone on isolated and cellular proteasomes .   FEBS JOURNAL   277( 9): 2128-2141

Bader M, Steller H.  2009. Regulation of cell death by the ubiquitin-proteasome system .  CURRENT OPINION IN CELL BIOLOGY.   21 (6): 878-884   

Sombroek D, Hofmann TG. 2009.  How cells switch HIPK2 on and off.   CELL DEATH AND DIFFERENTIATION  16 ( 2): 187-194

Haimerl F, Erhardt A, Sass G, et al.  2009.  Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-alpha-induced Hepatocyte Survival.  JOURNAL OF BIOLOGICAL CHEMISTRY.   284( 1): 495-504

Uvarov AV, Mesaeli N .  2008. Enhanced ubiquitin-proteasome activity in calreticulin deficient cells: A compensatory mechanism for cell survival.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH    1783( 6): 1237-1247  

Steller H.  2008. Regulation of apoptosis in DrosophilaCELL DEATH AND DIFFERENTIATION.  15(7): 1132-1138   

Ohsawa, S., Hamada, S., Yoshida, H., and Miura, M.  2008.  Caspase-mediate changes in hostone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neuronsCell Death and Differentiation.  15:1429-1439.

Schile AJ, Garcia-Fernandez M, Steller H  2008.  Regulation of apoptosis by XIAP ubiquitin-ligase activity.  GENES & DEVELOPMENT    22(16): 2256-2266 

Tsuruta T, Oh-hashi K, Kiuchi K, et al.  2008.  Degradation of caspase-activated DNase by the ubiquitin-proteasome system.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS.   1780( 5): 793-799   

Naujokat C, Fuchs D, Berges C. 2007. Adaptive modification and flexibility of the proteasome system in response to proteasome inhibition BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH.: 1773 ( 9): 1389-1397  

Mazroui R, Di Marco S, Kaufman RJ, et al. 2007.  Inhibition of the ubiquitin-proteasome system induces stress granule formation.   MOLECULAR BIOLOGY OF THE CELL.  18( 7): 2603-2618

Ryoo HD, Gorenc T and Stellar H.   2004.  Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.   Developmental Cell  7(4): 491-501

Arama E, Agapite J, Steller H.  2003.  Caspase activity and a specific cytochrome c are required for sperm differentiation in Drosophila .   DEVELOPMENTAL CELL.   4( 5): 687-697











Recommended Readings: Gerard Evan, Ph. D.

Friday Lecture Series

Deconstructing Oncogenesis and Tumor Suppression

to Find the Best Cancer Drug Targets

Gerard Evan, Ph.D., FRS,

Gerson and Barbara Bass Bakar Distinguished Professor in Cancer Research, University of California, San Francisco

May 14, 2010

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Amaravadi, R. K., D. Yu, J. J. Lum, T. Bui, M. A. Christophorou, G. I. Evan, A. Thomas-Tikhonenko, and C. B. Thompson. 2007. Autophagy inhibition enhances therapy-induced apoptosis in a myc-induced model of lymphoma. Journal of Clinical Investigation  117, (2): 326-336

Christophorou, M. A., I. Ringshausen, A. J. Finch, L. B. Swigart, and G. I. Evan. 2006. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 443, (7108): 214-217

Evan, G. I., Christophorou, M., Lawlor, E. A., Ringshausen, I., Prescott, J., Dansen, T., Finch, A., Martins, C., and Murphy, D. Oncogene-dependent tumor suppression: Using the dark side of the force for cancer therapy.2005

Lawlor, E. R., L. Soucek, L. Brown-Swigart, K. Shchors, C. U. Bialucha, and G. I. Evan. 2006. Reversible kinetic analysis of myc targets in vivo provides novel insights into myc-mediated tumorigenesis. Cancer research 66, (9): 4591-4601

Martins, C. P., L. Brown-Swigart, and G. I. Evan. 2006. Modeling the therapeutic efficacy of p53 restoration in tumors. Cell 127, (7): 1323-1334

Shchors, K., and G. Evan. 2007. Tumor angiogenesis: Cause or consequence of cancer? Cancer research 67, (15): 7059-7061

Recommended Readings: Tim White, Ph. D.

Friday Lecture Series

Fairfield Osborn Memorial Lecture

Human Evolution: The Six-Million-Year View from Afar

Tim White, Ph.D., professor,

University of California, Berkeley

May 7, 2010

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Clark, J. D., Y. Beyene, G. WoldeGabriel, W. K. Hart, P. R. Renne, H. Gilbert, A. Defieur, et al. 2003. Stratigraphic, chronological and behavioural contexts of pleistocene homo sapiens from middle awash, ethiopia. Nature 423, (6941): 747-752

Lovejoy, C. O., M. J. Cohn, and T. D. White. 1999. Morphological analysis of the mammalian postcranium: A developmental perspective. Proceedings of the National Academy of Sciences of the United States of America 96, (23): 13247-13252

White, T. 2003. Paleoanthropology. Early hominids–diversity or distortion? Science 299, (5615): 1994-1997

White, T. D. 2000. A view on the science: Physical anthropology at the millennium. American Journal of Physical Anthropology 113, (3): 287-292

White, T. D., G. WoldeGabriel, B. Asfaw, S. Ambrose, Y. Beyene, R. L. Bernor, J. -R Boisserie, et al. 2006. Asa issie, aramis and the origin of australopithecus. Nature 440, (7086): 883-889

Recommended Readings: Howard Hang, Ph.D. May 17, 2010

Monday Seminar Series

Discovery of Bacterial Virulence Inhibitors

From Plant Extracts

Howard Hang, Ph.D.,


Laboratory of Chemical Biology and Microbial Pathogenesis

May 17, 2010

3:45 p.m.-5:00 p.m.  Welch Hall Level two

Recommended Articles:

 Aiello D;  Williams JD; Majgier-Baranowska H, et al.   2010.  Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   54(5): 1988-1999   

Rasko DA; Sperandio V.   2010.  Anti-virulence strategies to combat bacteria-mediated disease .  NATURE REVIEWS DRUG DISCOVERY    9 (2): 117-128   

 Veenendaal AKJ;  Sundin C;  Blocker AJ.  2010.  Small-Molecule Type III Secretion System Inhibitors Block Assembly of the Shigella Type III Secreton .    JOURNAL OF BACTERIOLOGY     191(2):563-570   

 Pan NJ, Brady MJ, Leong JM, et al.   2009.  Targeting Type III Secretion in Yersinia pestis.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY     53(2): 385-392  

Raghavan AS, Hang HC .  2009  Seeing small molecules in action with bioorthogonal chemistry .  2009.
 DRUG DISCOVERY TODAY    14(3-4): 178-184    Request from Markus Library.

 Doring O;  Luthje S.   2001.  Inhibition of trans-membrane hexacyanoferrate III reductase activity and proton secretion of maize (Zea mays L.) roots by thenoyltrifluoroacetone .    PROTOPLASMA   217(1-3): 3-8      Request  from Markus Library.

Recommended Readings: Sean F. Brady Ph.D. May 10, 2010

Monday Seminar Series

Culture Independent Approaches for the

Discvoery of New Bacterial Metabolites

Sean F. Bady  Ph.D.,

Laboratory of Geneticall Encoded Small Molecules

Howard Hughes Medical Institute, The Rockefeller University

May 10, 2010

3:45 p.m.-5:00 p.m.  Welch Hall Level two


Recommended Articles:

 Simon, C;  Daniel, R.   2009.  Achievements and new knowledge unraveled by metagenomic approaches.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY    85(2): 265-276     Request from Markus Library.

 McAlpine, J. B.    2009.  Advances in the Understanding and Use of the Genomic Base of Microbial Secondary Metabolite Biosynthesis for the Discovery of New Natural Products.   JOURNAL OF NATURAL PRODUCTS,   72(3, Sp. Iss. SI): 566-572      Request from Markus Library.   

 Brady S.F; Simmons L;  Kim J.H. et al.   2009.  Metagenomic approaches to natural products from free-living and symbiotic organisms .   NATURAL PRODUCT REPORTS.    26(11): 1488-1503    Request from Markus Library.

 King, R. W.; Bauer, J. D.; Brady, S.F.    2009.  An Environmental DNA-Derived Type II Polyketide Biosynthetic Pathway Encodes the Biosynthesis of the Pentacyclic Polyketide ErdacinANGEWANDTE CHEMIE-INTERNATIONAL EDITION     48( 34): 6257-6261    

 Banik, J J; Brady, S. F.    2008.  Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary .  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.     105(45):17273-17277    

 Sharma P;  Kumari, H;  Kumar, M; Verna, M;  KUmariu K;  Malhotra, S;  Kurana, J; Lal, R.  2008.   From bacterial genomics to metagenomics: concept, tools and recent advances.   Indian Journal of Microbiology.  48(2);173-194.  Requesst from Markus Library.

  Brady SF, Bauer JD, Clarke-Pearson MF, et al.   2007. Natural products from isnA-containing biosynthetic gene clusters recovered from the genomes of cultured and uncultured bacteria.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.   129( 40): 12102-+