Recommended Readings: Christine Petit, M.D., Ph.D.

Friday Lecture Series

Understanding Hearing Mechanisms: Advances Rooted in the Genetic Approach

Christine Petit, M.D., Ph.D., professor,College de France;

Chair of Genetics & Cellular Physiology; head, Unit of Genetics and Physiology of Hearing,

Institut Pasteur

April 30, 2010

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Cohen-Salmon, M., B. Regnault, N. Cayet, D. Caille, K. Demuth, J. -P Hardelin, N. Janel, P. Meda, and C. Petit. 2007. Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis. Proceedings of the National Academy of Sciences of the United States of America 104, (15): 6229-6234

Lagresle-Peyrou, C., E. M. Six, C. Picard, F. Rieux-Laucat, V. Michel, A. Ditadi, C. D. -D Chappedelaine, et al. 2009. Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nature genetics 41, (1): 106-111

Petit, C. 2006. From deafness genes to hearing mechanisms: Harmony and counterpoint. Trends in molecular medicine 12, (2): 57-64

Roux, I., S. Safieddine, R. Nouvian, M. Grati, M. -C Simmler, A. Bahloul, I. Perfettini, et al. 2006. Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell 127, (2): 277-289

Wei, D., S. Levic, L. Nie, W. -Q Gao, C. Petit, E. G. Jones, and E. N. Yamoah. 2008. Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage. Proceedings of the National Academy of Sciences of the United States of America 105, (52): 21000-21005

Recommended Readings: Eric Davidson, Ph.D.

Friday Lecture Series

Detlev W. Bronk Alumni Lecture

Modularity and Design Principles in the Sea Urchin Embryo Gene Regulatory Network

Eric Davidson, Ph.D., Norman Chandler Professor of Cell Biology, division of biology,

California Institute of Technology

April 23, 2010

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Erwin, D. H., and E. H. Davidson. 2009. The evolution of hierarchical gene regulatory networks. Nature Reviews Genetics 10, (2): 141-148

Revilla-I-Domingo, R., P. Oliveri, and E. H. Davidson. 2007. A missing link in the sea urchin embryo gene regulatory network: HesC and the double-negative specification of micromeres. Proceedings of the National Academy of Sciences of the United States of America 104, (30): 12383-12388

Smith, J., and E. H. Davidson. 2008. Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo. Proceedings of the National Academy of Sciences of the United States of America 105, (51): 20089-20094

Smith, J., E. Kraemer, H. Liu, C. Theodoris, and E. Davidson. 2008. A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo. Developmental biology 313, (2): 863-875

Wahl, M. E., J. Hahn, K. Gora, E. H. Davidson, and P. Oliveri. 2009. The cis-regulatory system of the tbrain gene: Alternative use of multiple modules to promote skeletogenic expression in the sea urchin embryo. Developmental biology 335, (2): 428-441

Recommended Readings: Bert Hölldobler, Dr. rer.nat.

Friday Lecture Series

The Superorganism: Communication and Cooperation in Ant Societies

Bert Hölldobler, Dr. rer. nat., Dr. habil., Foundation Professor,

Arizona State University

April 16, 2010

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings:

Federle, W., E. L. Brainerd, T. A. McMahon, and B. Hölldobler. 2001. Biomechanics of the movable pretarsal adhesive organ in ants and bees. Proceedings of the National Academy of Sciences of the United States of America 98, (11): 6215-6220

Liebig, J., C. Peeters, N. J. Oldham, C. Markstädter, and B. Hölldobler. 2000. Are variations in cuticular hydrocarbons of queens and workers a reliable signal of fertility in the ant harpegnathos saltator? Proceedings of the National Academy of Sciences of the United States of America 97, (8): 4124-4131

Reeve, H. K., and B. Hölldobler. 2007. The emergence of a superorganism through intergroup competition. Proceedings of the National Academy of Sciences of the United States of America 104, (23): 9736-9740

Wilson, E. O., and B. Hölldobler. 2005. Eusociality: Origin and consequences. Proceedings of the National Academy of Sciences of the United States of America 102, (38): 13367-13371

Wilson, E. O., and B. Hölldobler. 2005. The rise of the ants: A phylogenetic and ecological explanation. Proceedings of the National Academy of Sciences of the United States of America  102, (21): 7411-7414

Recommended Readings: Jeffrey Ravetch M.D., Ph.D. Monday April 19, 2010

Monday Seminar Series

The Antibody Paradox: Novel Roles for Fc Glycans

Jeffrey Ravetch M.D., Ph.D.,

Theresa and Eugene M. Lang Professor
Leonard Wagner Laboratory of Molecular Genetics and Immunology

The Rockefeller University

April 19, 2010

3:45 p.m.-5:00 p.m.  Welch Hall Level two

 Recommended Readings:

 Ravetch J.  2010. In vivo veritas: the surprising roles of Fc receptors in immunity.   NATURE IMMUNOLOGY   11(3): 183-185.

Syam S, Mero P, Pham T, et al.  2010.  Differential Recruitment of Activating and Inhibitory Fc gamma RII during Phagocytosis.  JOURNAL OF IMMUNOLOGY  184( 6):2966- 2973 .  

van de Winkel JGJ.  2010.  Fc receptors: Role in biology and antibody therapy.   IMMUNOLOGY LETTERS  128(Special issue S1): 4-5.

Crispin M, Bowden TA, Coles CH, et al.  2009.  Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions.   JOURNAL OF MOLECULAR BIOLOGY  387(5):1061-1066.  

Jovanovic V, Dai XL, Lim YT, et al.  2009.  Fc gamma receptor biology and systemic lupus erythematosus. INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES   12(4):293-298.

 Anthony RM, Wermeling F, Karlsson MCI, et al.  2008.  Identification of a receptor required for the anti-inflammatory activity of IVIG.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   105(50):19571-19578.

 Nimmerjahn F, Ravetch JV.  2008,  Fc gamma receptors as regulators of immune responses.  NATURE REVIEWS IMMUNOLOGY   8 (1):34-47.

 Raju TS.  2008. Terminal sugars of Fc glycans influence antibody effector functions of IgGs.  CURRENT OPINION IN IMMUNOLOGY   20(4):471-478.

Nimmerjahn F, Ravetch JV.  2007.   Fc-receptors as regulators of immunity.  ADVANCES IN IMMUNOLOGY  (book series)    96:179-204