Recommended Readings: Eddy De Robertis, Ph.D., Nov 13, 2009

Friday Lecture Series

From Spemann’s Organizer to the Integration of BMP and Wnt Signaling Gradients in Embryos

Eddy De Robertis, M.D.,  Ph.D.

Norman Sprague Professor of Biological Chemistry, University of California, Los Angeles; investigator, Howard Hughes Medical Institute

November 13, 2009

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Articles:

De Robertis, E. M. 2006. Spemann’s organizer and self-regulation in amphibian embryos. Nature Reviews Molecular Cell Biology 7, (4): 296-302

De Robertis, E. M., and Kuroda, H. 2004.  Dorsal-ventral patterning and neural induction in xenopus embryos. Annual Review of Cell and Developmental Biology, 20: 285-308

Fuentealba, L. C., E. Eivers, A. Ikeda, C. Hurtado, H. Kuroda, E. M. Pera, and E. M. De Robertis. 2007. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 131, (5): 980-993

Lee, H. X., A. L. Ambrosio, B. Reversade, and E. M. De Robertis. 2006. Embryonic dorsal-ventral signaling: Secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell, 124, (1): 147-159

Reversade, B., and E. M. De Robertis. 2005. Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. Cell 123, (6): 1147-1160

Recommended Readings: Vincent A. Fischetti PhD Nov 23, 2009

Monday Lecture


Using What Phage have Learned to Kill Gram-positive Bacteria

Vincent A. Fischetti PhD

Laboratory of Bacterial Pathogenesis and Immunology

Rockefeller University

Nov. 23, 2009

Welch Hall, Level Two

Recommended Readings: 

O’Flaherty S, Ross RP, Coffey A .  2009.  Bacteriophage and their lysins for elimination of infectious bacteria.   FEMS MICROBIOLOGY REVIEWS    33(4):801-819  

Frias MJ, Melo-Cristino J, Ramirez M. 2009. The Autolysin LytA Contributes to Efficient Bacteriophage Progeny Release in Streptococcus pneumoniae.  JOURNAL OF BACTERIOLOGY   191(17):5428-5440  

 Fischetti VA.  2008.   Bacteriophage lysins as effective antibacterials.  CURRENT OPINION IN MICROBIOLOGY  11(5):393-400    

Raz A, Fischetti VA.  2008.  Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105(47):18549-18554     

 Celia LK, Nelson D, Kerr DE.  2008.  Characterization of a bacteriophage lysin (Ply700) from Streptococcus uberis.  VETERINARY MICROBIOLOGY  130(1-2):107-117   Request this article from Markus Library

 Fischetti VA.  2007.  Harnessing the host response for antiinfective therapy.  INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS  29(Supple 2):S97-S97   Request this article from Markus Library.

 Rotem S, Radzishevsky I, Inouye RT, et al.  2006.  Identification of antimicrobial peptide regions derived from genomic sequences of phage lysins.  PEPTIDES  27(1):18-26   Request this article from Markus Library.

 Cheng Q, Nelson D, Zhu SW, Fischetti VA.  2005.  Removal of group B streptococci colonizing the vagina and oropharynx of mice with a bacteriophage, lytic enzyme.  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   49(1):111-117  

 Jado I, Lopez R, Garcia E, et al.  2003.  Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY   52(6):967-973