Recommended Readings: Songon An, Ph.D. Sept. 30, 2009

Wednesday Lecture

Chemical Biology of a Metabolic Multi-enzyme Complex in Cells:

the “Purinosome”

Songon An  Ph.D.

Postdoctoral Scholar

Pennsylvania State University, Department of Chemistry

Sept. 30, 2009

4:00 p.m. (Refreshments, 3:45 p.m.)

Welch Hall, Level Two

Recommended Articles:

An SG, Kumar R, Sheets ED, et al.  2008.  Reversible compartmentalization of de novo purine biosynthetic complexes in living cells. SCIENCE. 320 (5872): 103-106

DeLisa MP, Conrado RJ.  2009.  Synthetic metabolic pipelines.  NATURE BIOTECHNOLOGY. 27 (8): 728-729

Dueber JE , Wu GC, Malmirchegini GR, Moon TS, Petzold CJ, Ullal AV, Keasling JD.  2009.  Synthetic protein scaffolds provide modular control over metabolic flux. NATURE BIOTECHNOLOGY. 27 (8): 753-U107

Zhang Y, Morar M, Ealick SE.  2008.  Structural biology of the purine biosynthetic pathway. CELLULAR AND MOLECULAR LIFE SCIENCES 65 (23): 3699-3724    Request article from  Markus Library.

Conrado RJ, Varner JD, DeLisa MP.  2008.  Engineering the spatial organization of metabolic enzymes: mimicking nature’s synergy. CURRENT OPINION IN BIOTECHNOLOGY. 19 (5): 492-499