Investigating Tumor Maintenance and miRNA Biology in Mice
Monday, February 25, 2008
Welch Hall (2nd Floor)
3:45 p.m. Refreshments 4:00 p.m. Lecture
Figure 2. p53 restoration leads to tumour regression in vivo. From Ventura et al. (2007) Nature 445:661-665.
Related Articles
Fuster, J. J., Sanz-Gonzalez, S. M., Moll, U. M. and Andres, V. (2007). Classic and novel roles of p53: prospects for anticancer therapy. Trends in Molecular Medicine 13:192-199.
He, L., He, X. Y., Lowe, S. W. and Hannon, G. J. (2007). microRNAs join the p53 network – another piece in the tumour-suppression puzzle. Nature Reviews Cancer 7:819-822.
Ventura, A., Kirsch, D. G., McLaughlin, M. E., Tuveson, D. A., Grimm, J., Lintault, L., Newman, J., Reczek, E. E., Weissleder, R. and Jacks, T. (2007). Restoration of p53 function leads to tumour regression in vivo. Nature 445:661-665.
Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C. and Lowe, S. W. (2007). Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445:656-660.
Zhang, B. H., Pan, X. P., Cobb, G. P. and Anderson, T. A. (2007). microRNAs as oncogenes and tumor suppressors. Developmental Biology 302:1-12.
