Related Readings – Monday Lecture – Cori Bargmann, Ph.D.

Thirteen Ways of Looking at a Synapse

Monday, October 29, 2007
Welch Hall (2nd Floor)

3:45 p.m. Refreshments 4:00 p.m. Lecture

Recommended Review Article

Bargmann, C. I. (2006). Comparative chemosensation from receptors to ecology. Nature 444:295-301.

Related Articles

Chang, A. J., Chronis, N., Karow, D. S., Marletta, M. A. and Bargmann, C. I. (2006). A distributed chemosensory circuit for oxygen preference in C-elegans. PLoS Biology 4:1588-1602.
Chronis, N., Zimmer, M. and Bargmann, C. I. (2007). Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans. Nature Methods 4:727-731.
Chuang, C. F., VanHoven, M. K., Fetter, R. D., Verselis, V. K. and Bargmann, C. I. (2007). An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans. Cell 129:787-799.
Patel, M. R., Lehrman, E. K., Poon, V. Y., Crump, J. G., Zhen, M., Bargmann, C. I. and Shen, K. (2006). Hierarchical assembly of presynaptic components in defined C. elegans synapses. Nature Neuroscience 9:1488-1498.

Related Readings – Friday Lecture – Timothy A. Ryan, Ph.D.

The Synaptic Vesicle Cycle: Deciphering the Molecules and Membrane Traffic that Support Neurotransmission

Friday, October 26, 2007

Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge

Recommended Review Article

Sudhof, T. C. (2004). The synaptic vesicle cycle. Annual Review of Neuroscience 27:509-547.

Related Articles

Ferguson, S. M., Brasnjo, G., Hayashi, M., Wolfel, M., Collesi, C., Giovedi, S., Raimondi, A., Gong, L. W., Ariel, P., Paradise, S., O’Toole, E., Flavell, R., Cremona, O., Miesenbock, G., Ryan, T. A. and De Camilli, P. (2007). A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science 316:570-574.
Fernandez-Alfonso, T., Kwan, R. and Ryan, T. A. (2006). Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling. Neuron 51:179-186.
Ryan, T. A. (2006). A pre-synaptic to-do list for coupling exocytosis to endocytosis. Current Opinion in Cell Biology 18:416-421.
Schweizer, F. E. and Ryan, T. A. (2006). The synaptic vesicle: cycle of exocytosis and endocytosis. Current Opinion in Neurobiology 16:298-304.
Willig, K. I., Rizzoli, S. O., Westphal, V., Jahn, R. and Hell, S. W. (2006). STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature 440:935-939.

Related Readings – Monday Lecture – Paul Greengard, Ph.D.

Signal Transduction Pathways Used and Abused by CNS Drugs

Monday, October 22, 2007
Welch Hall (2nd Floor)

3:45 p.m. Refreshments 4:00 p.m. Lecture

Recommended Review Article

Svenningsson, P., Nishi, A., Fisone, G., Girault, J. A., Nairn, A. C. and Greengard, P. (2004). DARPP-32: An integrator of neurotransmission. Annual Review of Pharmacology and Toxicology 44:269-296.

Related Articles

Borgkvist, A., Usiello, A., Greengard, P. and Fisone, G. (2007). Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward. Neuropsychopharmacology 32:1995-2003.
Nairn, A. C., Svenningsson, P., Nishi, A., Fisone, G., Girault, J. A. and Greengard, P. (2004). The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology 47:14-23.
Nishi, A., Watanabe, Y., Higashi, H., Tanaka, M., Nairn, A. C. and Greengard, P. (2005). Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proceedings of the National Academy of Sciences of the United States of America 102:1199-1204.
Santini, E., Valjent, E., Usiello, A., Carta, M., Borgkvist, A., Girault, J. A., Herve, D., Greengard, P. and Fisone, G. (2007). Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia. Journal of Neuroscience 27:6995-7005.
Svenningsson, P. and Greengard, P. (2006). A master regulator in the brain. The Scientist 20:40-47.

Related Readings – Friday Lecture – Michael Snyder, Ph.D.

Analyzing Differences Between Individuals and Between Species

Friday, October 19, 2007

Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge

Recommended Review Article

Zhu, X. W., Gerstein, M. and Snyder, M. (2007).Getting connected: analysis and principles of biological networks. Genes & Development 21:1010-1024.

Related Articles

Borneman, A. R., Gianoulis, T. A., Zhang, Z. D. D., Yu, H. Y., Rozowsky, J., Seringhaus, M. R., Wang, L. Y., Gerstein, M. and Snyder, M. (2007).Divergence of transcription factor binding sites across related yeast species. Science 317:815-819.

Korbel, J. O., Urban, A. E., Grubert, F., Du, J., Royce, T. E., Starr, P., Zhong, G. N., Emanuel, B. S., Weissman, S. M., Snyder, M. and Gerstein, M. B. (2007).Systematic prediction and validation of breakpoints associated with copy-number variants in the human genome. Proceedings of the National Academy of Sciences of the United States of America 104:10110-10115.

Kung, L. A. and Snyder, M. (2006).Proteome chips for whole-organism assays. Nature Reviews Molecular Cell Biology 7:617-622.

Ren, B., Robert, F., Wyrick, J. J., Aparicio, O., Jennings, E. G., Simon, I., Zeitlinger, J., Schreiber, J., Hannett, N., Kanin, E., Volkert, T. L., Wilson, C. J., Bell, S. P. and Young, R. A. (2000).Genome-wide location and function of DNA binding proteins. Science 290:2306.

Related Readings – Friday Lecture – Blaise Aguera y Arcas

Visual Swarms

Friday, October 12, 2007

Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge

Related Articles and Videos/Websites

TED Talks. (Filmed Mar 2007; Posted May 2007). Blaise Aguera y Arcas: Jaw-dropping Photosynth demo [Video]. TED2007; 2007 Mar 7-10; Monterey, CA.
Microsoft Live Labs. (2006). Photosynth [Website].
Snavely, N., Seitz, S.M. and Szeliski, R. (2006). Photo tourism: Exploring photo collections in 3D. ACM Transactions on Graphics (SIGGRAPH Proceedings) 25:835-846.
University of Washington. (2006). Photo tourism: Exploring photo collections in 3D [Website].

Related Readings – Friday Lecture – Allan C. Spradling, Ph.D.

Modeling Aspects of Mammalian Reproductive Biology Using the Drosophila Ovary

Friday, October 5, 2007

Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge

Recommended Review Article

Qazi, M. C. B., Heifetz, Y. and Wolfner, M. F. (2003). The developments between gametogenesis and fertilization: ovulation and female sperm storage in Drosophila melanogaster. Developmental Biology 256:195-211.

Related Articles

Decotto, E. and Spradling, A. C. (2005). The Drosophila ovarian and testis stem cell niches: Similar somatic stem cells and signals. Developmental Cell 9:501-510.
Fuller, M. T. and Spradling, A. C. (2007). Male and female Drosophila germline stem cells: Two versions of immortality. Science 316:402-404.
Gilboa, L., and Lehmann, R. (2007). Changing places: A novel type of niche and stem cell coordination in the Drosophila ovary. Cell Stem Cell 1:239-240.
Nystul, T., and Spradling, A. (2007) An epithelial niche in the Drosophila ovary undergoes long-range stem cell replacement. Cell Stem Cell 1:277-285.