Related Readings – Monday Lecture – Titia de Lange Ph.D.

How telomeres deal with the DNA damage response

Monday, April 23, 2007
Welch Hall (2nd Floor)

3:45 p.m. Refreshments 4:00 p.m. Lecture

Recommended Overview Article

de Lange, T. (Article Online Posting Date: September 23, 2005).Telomeres: Protection and Maintenance. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd.

Related Articles

Celli, G. B. and de Lange, T. (2005).DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nature Cell Biology 7:712-U110.
de Lange, T. (2004).T-loops and the origin of telomeres. Nature Reviews Molecular Cell Biology 5:323-329.
de Lange, T. (2005).Shelterin: the protein complex that shapes and safeguards human telomeres. Genes & Development 19:2100-2110.
d’Adda di Fagagna, F., Teo, S. H. and Jackson, S. P. (2004). Functional links between telomeres and proteins of the DNA-damage response. Genes & Development 18:1781-1799.
Dimitrova, N. and de Lange, T. (2006).MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres. Genes & Development 20:3238-3243.

Related Readings – Friday Lecture – Alexander Rudensky Ph.D.

Dominant Tolerance

Friday, April 20, 2007

Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge

Recommended Review Article

Related Articles

Gavin, M. A., Rasmussen, J. P., Fontenot, J. D., Vasta, V., Manganiello, V. C., Beavo, J. A. and Rudensky, A. Y. (2007).Foxp3-dependent programme of regulatory T-cell differentiation. Nature 445:771-775.
Kim, J. M. and Rudensky, A. (2006).The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunological Reviews 212:86-98.
Sakaguchi, S., Ono, M., Setoguchi, R., Yagi, H., Hori, S., Fehervari, Z., Shimizu, J., Takahashi, T. and Nomura, T. (2006).Foxp3(+)CD25(+)CD4(+) natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunological Reviews 212:8-27.
Schwartz, R. H. (2005).Natural regulatory T cells and self-tolerance. Nature Immunology 6:327-330.