Understanding Protein Folding in the Cell – F. Ulrich Hartl, M.D.
Chaperonin-Mediated Protein Folding – Arthur L. Horwich, M.D.
Friday, April 6, 2007
Caspary Auditorium 3:45 p.m. – 5:15 p.m. Tea at 3:15 p.m. in the Abby Lounge
Recommended Overview Article
Ellis, R. John and Hartl, F. Ulrich. (Article Online Posting Date: January 27, 2006).Protein folding and chaperones. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd.
Barral, J. M., Broadley, S. A., Schaffar, G. and Hartl, F. U. (2004).Roles of molecular chaperones in protein misfolding diseases. Seminars in Cell & Developmental Biology 15:17-29.
Bukau, B., Weissman, J. and Horwich, A. (2006).Molecular chaperones and protein quality control. Cell 125:443-451.
Hartl, F. U. (1996).Molecular chaperones in cellular protein folding. Nature 381:571-580.
Horwich, A. L., Farr, G. W. and Fenton, W. A. (2006).GroEL-GroES-mediated protein folding. Chemical Reviews 106:1917-1930.
Park, E. S., Fenton, W. A. and Horwich, A. L. (2007).Disulfide formation as a probe of folding in GroEL-GroES reveals correct formation of long-range bonds and editing of incorrect short-range ones. Proceedings of the National Academy of Sciences of the United States of America 104:2145-2150.
Young, J. C., Agashe, V. R., Siegers, K. and Hartl, F. U. (2004).Pathways of chaperone-mediated protein folding in the cytosol. Nature Reviews Molecular Cell Biology 5:781-791.