Recommended Readings: Tania Baker Ph.D. Friday, November 18, 2016

Friday Lectures

Friday, November 18, 2016   3:45 p.m.

Caspary Auditorium

Tania Baker, Ph.D.

Edwin C. Whitehead Professor of Biology, MIT

Investigator, HHMI

Operations of AAA+ Unfoldase Motors:

Powerful Destroyers and Activators of Protein Function

Selected Publications:

Baker, Tania A.; Sauer, Robert T.  ClpXP, an ATP-powered unfolding and protein-degradation machine.    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH.   1823(Special Issue SI): 15-28     JAN 2012

Stinson, Benjamin M.; Nager, Andrew R.; Glynn, Steven E.; et al.  Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA plus Machine. CELL   153(3):628-639    APR 25 2013

Glynn, Steven E.; Nager, Andrew R.; Baker, Tania A.; et al.   Dynamic and static components power unfolding in topologically closed rings of a AAA plus proteolytic machine.   NATURE STRUCTURAL & MOLECULAR BIOLOGY.  19(6):616-+   JUN 2012

Cordova, Juan Carlos; Olivares, Adrian O.; Shin, Yongdae; et al.    Stochastic but Highly Coordinated Protein Unfolding and Translocation by the ClpXP Proteolytic Machine.  CELL    158(3): 647-658     JUL 31 2014

Olivares, Adrian O.; Nager, Andrew R.; Iosefson, Ohad; et al.   Mechanochemical basis of protein degradation by a double-ring AAA plus machine.   NATURE STRUCTURAL & MOLECULAR BIOLOGY    21(10): 871-875    OCT 2014

 

Recommended Readings: Frederick Cross Ph.D. Monday December 5, 2016

Monday Lectures

 December 5, 2016

4:00 p.m.  Carson Family Auditorium  CRC

Frederick Cross  Ph.D.

Professor,  Laboratory of Cell Cycle Genetics

The Rockefeller University

Evolution of Cell Cycle Control:

Branches and a Green Microbe

Recommended Readings:

Tulin, Frej; Cross, Frederick R.  Patching Holes in the Chlamydomonas Genome.  G3-GENES GENOMES GENETICS   6(7): 1899-1910   JUL 1 2016

Onishi, Masayuki; Pringle, John R.; Cross, Frederick R.   Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin Integrity in Chlamydomonas.  GENETICS    202(30): 977-+  MAR 2016

Tulin, Frej; Cross, Frederick R.   A Microbial Avenue to Cell Cycle Control in the Plant Superkingdom.   PLANT CELL   26(10): 4019-4038     OCT 2014

Cross, Frederick R.; Umen, James G.  The Chlamydomonas cell cycle   PLANT JOURNAL   82(3): 370-392   MAY 2015

Recommended Readings: Michael O’Donnell Ph.D. Monday December 12, 2016

Monday Lectures

 December 12, 2016

4:00 p.m.  Carson Family Auditorium  CRC

Michael O’Donnell  Ph.D.

HHMI Investigator, and Anthony and Judith Evnin Professor
Laboratory of DNA Replication

The Rockefeller University

The Eukaryotic Replisome

Recommended Readings:

O’Donnell, Mike; Li, Huilin   The Eukaryotic Replisome Goes Under the Microscope.  CURRENT BIOLOGY  26(6): R247-R256      MAR 21 2016

Yuan, Zuanning; Bai, Lin; Sun, Jingchuan; et al.   Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.  NATURE STRUCTURAL & MOLECULAR BIOLOGY   23(3): 217-224     MAR 2016

Sun, Jingchuan; Shi, Yi; Georgescu, Roxana E.; et al.   The architecture of a eukaryotic replisome.   NATURE STRUCTURAL & MOLECULAR BIOLOGY    22(12): 976-982 DEC 2015

Georgescu, Roxana E.; Schauer, Grant D.; Yao, Nina Y.; et al.  Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.      ELIFE    4: e04988     APR 14 2015

O’Donnell, Michael; Langston, Lance; Stillman, Bruce  Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya .   COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY    5(7): a010108

Recommended Readings: Eric N. Olson Ph.D. Friday December 2, 2016

Friday Lecture Series

 December 2, 2016

3:45 p.m. (refreshments 3:15)  Caspary Auditorium

Eric N. Olson, Ph.D.

Founding Chair, Department of Molecular Biology.

University of Texas Southwestern Medical Center

The Molecules and Mechanisms of Muscle Development,

Disease and Regeneration

Recommended Readings:

Shadrin, I. Y.; Khodabukus, A.; Bursac, N.   Striated muscle function, regeneration, and repair.  CELLULAR AND MOLECULAR LIFE SCIENCES.    73(22):4175-4202   NOV 2016

McCullagh, Karl J. A.; Perlingeiro, Rita C. R.  Coaxing stem cells for skeletal muscle repair.  ADVANCED DRUG DELIVERY REVIEWS    84: 198-207   APR 2015  REQUEST FROM MARKUS LIBRARY

Juhas, Mark; Bursac, Nenad   Engineering skeletal muscle repair.  CURRENT OPINION IN BIOTECHNOLOGY    24(5): 880-886    OCT 2013

Garbern, Jessica C.; Lee, Richard T.    Cardiac Stem Cell Therapy and the Promise of Heart Regeneration.  CELL STEM CELL  12(6): 689-698   JUN 6 2013 

Xin, Mei; Olson, Eric N.; Bassel-Duby, Rhonda   Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair.  NATURE REVIEWS MOLECULAR CELL BIOLOGY     14(8): 529-541    AUG 2013

Nicklas, Sarah; Otto, Anthony; Wu, Xiaoli; et al.   TRIM32 Regulates Skeletal Muscle Stem Cell Differentiation and Is Necessary for Normal Adult Muscle Regeneration.  PLOS ONE   7 (1): e30445    JAN 27 2012  

Recommended Readings: Jennifer A. Zallen Ph.D. Friday November 11, 2016

Friday Lectures

Frfday, November 11, 2016   3:45 p.m.

Caspary Auditorium

Jennifer A. Zallen, Ph.D.

HHMI Investigator / Member, Sloan Kettering Institute

Signals and Forces that Control Multicellular

Organization in the Embryo

Recommended Readings:

Mao, Qiyan; Lecuit, Thomas    Mechanochemical Interplay Drives Polarization in Cellular and Developmental Systems.  Book Series: Current Topics in Developmental Biology   Volume:116   Pages: 633-+    2016   Edited by: Wassarman, PM

Gouti, Mina; Metzis, Vicki; Briscoe, James.  The route to spinal cord cell types: a tale of signals and switches.TRENDS IN GENETICS   31(6): 282-289   Published: JUN 2015

Uriu, Koichiro; Morelli, Luis G.; Oates, Andrew C.  Interplay between intercellular signaling and cell movement in development.  SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY    35: 66-72      NOV 2014

Neijts, Roel; Simmini, Salvatore; Giuliani, Fabrizio; et al   Region-Specific Regulation of Posterior Axial Elongation During Vertebrate Embryogenesis.  DEVELOPMENTAL DYNAMICS   243(1. Special Issue: SI): 88-98    JAN 2014

 Zallen, Jennifer A.; Blankenship, J. Todd   Multicellular dynamics during epithelial elongation.  SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY.   19(3): 263-270 : JUN 2008

Recommended Readings: Marcello Magnasco Ph.D. Monday October 31, 2016

Monday Lectures

Monday October 31, 2016   3:45 p.m.

Caspary Auditorium

Marcello Magnasco, Ph.D.

Professor, Mathematical Physics

The Rockefeller University

Recommended Readings:

Janik VM, and Slater PJB.  Vocal Learning in Mammals.  Advances in the Study of Behavior,   26:59-99     1997    Request through Markus Library at librequest@rockefeller.edu

Reiss D, and McCowan B.  Spontaneous Vocal Mimicry and Production by Bottle-nosed Dolphins (Tursiops truncatus) – evidence for vocal learning.   Journal of Comparative Psychology   107(3):301-312    Sept  1997

McCowan B, Hanser SF, and Doyle LR.  Quantitative Tools for Comparing Animal Communication Systems: information theory applied to bottlenose dolphin whistle repertoires.  Animal Behavior.  57:409-419    Feb 1999

Janik VM.  Cetacean Vocal Learning and Communication.  Current Opinion in Neurobiology.  28:60-65    Oct 2014

Luis AR, Couchinho MN, and dos Santos ME.   Quantitative Analysis of Pulsed Signals Emitted by Wild Bottlenose Dolphins.  PLoS One   11(7):e0157781      July 2016

Gruden P, White PR, Oswald JN, Barkley Y, Cerchio S, Lammers M,and  Baumann-Pickering S.   Differences in Oscillatory Whistles Produced by Spinner (Stenella longirostris) and Pantropical Spotted (Stenella attenuata) Dolphins.   Marine Mammal Science  32:520-534    April 2016

Recommended Readings: Nicole King Ph.D. October 7 2016

Friday Lecture Series

Friday October 7, 2016   3:45 p.m.

The Fairfield Osborn Memorial Lecture

Caspary Auditorium

Nicole King

Professor, and HHMI Investigator

Dept.of Molecular and Cell Biology, Division of Genetics, Genomics and Development

University of California Berkeley

Bacteria as Master Regulators and Aphrodisiacs

Recommended Readings:

Anderson, Douglas P.; Whitney, Dustin S.; Hanson-Smith, Victor; et al.  Evolution of an ancient protein function involved in organized multicellularity in animals. ELIFE                   5: e10147    JAN 7 2016

Alegado, Rosanna A.; King, Nicole  Bacterial Influences on Animal OriginsCOLD SPRING HARBOR PERSPECTIVES IN BIOLOGY    6(11): a016162  NOV 2014

King, Nicole.  Evolutionary Transitions to Multicellular Life Principles and Mechanisms Forrward.  EVOLUTIONARY TRANSITIONS TO MULTICELLULAR LIFE: PRINCIPLES AND MECHANISMS   Book Series:Advances in Marine Genomics   Volume: 2   Pages: V-VI    2015

King, Nicole; Mueller, Susann.  Environmental microbiology: Revisiting the physiology of microorganisms on the single cell scale. CURRENT OPINION IN MICROBIOLOGY     Volume: 25   Pages: V-VI   Published: JUN 2015

Recommended Readings: Uri Alon Ph.D. October 28 2016

Friday Lecture Series

Friday  October 28  2016    3:45  p.m.

Caspary Auditorium

Uri Alon

Professor, Department of Molecular Cell Biology

Weizmann Institute of Science

Evolutionary Trade Offs and the Geometry of Phenotype Space

Recommended Readings:

Keren, Leeat; Hausser, Jean; Lotan-Pompan, Maya; et al. Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness. CELL    166(5):1282-+  AUG 25 2016

Korem, Yael; Szekely, Pablo; Hart, Yuval; et al. Geometry of the Gene Expression Space of Individual Cells. PLOS COMPUTATIONAL BIOLOGY    11(7):e1004224   JUL 2015

Tendler, Avichai; Mayo, Avraham; Alon, Uri  Evolutionary tradeoffs, Pareto optimality and the morphology of ammonite shells. BMC SYSTEMS BIOLOGY  V 9: article number: 12   MAR 7 2015

Szekely, Pablo; Sheftel, Hila; Mayo, Avi; et al. Evolutionary Tradeoffs between Economy and Effectiveness in Biological Homeostasis Systems.  PLOS COMPUTATIONAL BIOLOGY.   9(8): e1003163    AUG 2013

Sheftel, Hila; Shoval, Oren; Mayo, Avi; et al. The geometry of the Pareto front in biological phenotype space. ECOLOGY AND EVOLUTION.   3(6):1471-1483    JUN 2013

Recommended Readings: Rebecca Saxe Ph.D. October 21, 2016

Friday Lecture Series

Friday October 21, 2016   3:45 p.m.

Caspary Auditorium

Rebecca Saxe, Ph.D.

Professor, MIT, Brain and Cognitive Sciences

It’s the Thought that counts: Progress in understanding the 

Neural basis of Theory of Mind

Recommended Readings:

 Chakroff, Alek; Dungan, James; Koster-Hale, Jorie; et al.  When minds matter for moral judgment: intent information is neurally encoded for harmful but not impure acts. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE   11(3):476-484    MARCH 2016

Jacoby, Nir; Bruneau, Emile; Koster-Hale, Jorie; et al.  Localizing Pain Matrix and Theory of Mind networks with both verbal and non-verbal stimuli. NEUROIMAGE  126:39-48     FEB 1 2016

Deen, Ben; Koldewyn, Kami; Kanwisher, Nancy; et al.  Functional Organization of Social Perception and Cognition in the Superior Temporal Sulcus. CEREBRAL CORTEX    25(11):4596-4609     NOV 2015

Bruneau, Emile G.; Cikara, Mina; Saxe, Rebecca.  Minding the Gap: Narrative Descriptions about Mental States Attenuate Parochial Empathy.  PLOS ONE                 10:e0140838     OCT 27 2015

Andrews-Hanna, Jessica R.; Saxe, Rebecca; Yarkoni, Tal   Contributions of episodic retrieval and mentalizing to autobiographical thought: Evidence from functional neuroimaging, resting-state connectivity, and fMRI meta-analyses. NEUROIMAGE   91:324-335   MAY 1 2014

Koster-Hale, Jorie; Saxe, Rebecca; Dungan, James; et al.  Decoding moral judgments from neural representations of intentions. PNAS   110(14): 5648-5653   APRIL 2 2013

Recommended Readings: Ole Kiehn Ph.D. October 14, 2016

Friday Lecture Series

Friday October 14, 2016   3:45 p.m.

Caspary Auditorium

Ole Kiehn, Ph.D.

Professor, Mammalian Locomotor Laboratory,

Dept. of Neuroscience, Karolinska Institut

Deciphering the Functional Organization of Neuronal Circuits

Controlling Locomotion

Recommended Readings:

Kiehn, Ole.  Decoding the organization of spinal circuits that control locomotion. NATURE REVIEWS NEUROSCIENCE    17(4): 224-238    APR 2016

Bouvier, Julien; Caggiano, Vittorio; Leiras, Roberto; et al. Descending Command Neurons in the Brainstem that Halt Locomotion. CELL   163(5): 1191-1203    NOV 19 2015

Patrick, Susan K.; Noah, J. Adam; Yang, Jaynie F.   Interlimb Coordination in Human Crawling Reveals Similarities in Development and Neural Control With Quadrupeds.JOURNAL OF NEUROPHYSIOLOGY   101(2): 603-613   FEB 2009

Stuart, Douglas G.; Hultborn, Hans. Thomas Graham Brown (1882-1965), Anders Lundberg (1920-), and the neural control of stepping. BRAIN RESEARCH REVIEWS  59(1) : 74-95   NOV 2008