Recommended Readings: Talia Lerner, Ph.D., March 10

Special Lecture Series
Thursday, March 10, 2016
4:00 p.m., Carson Family Auditorium (CRC)

Talia Lerner, Ph.D.
Postdoctoral Fellow,
Department of Bioengineering,
Stanford University

Distinct Information Encoding in Circuit-Defined Nigrostriatal Dopamine Neuron Subpopulations

Recommended Reading

Adhikari, A., Lerner, T. N., Finkelstein, J., Pak, S., Jennings, J. H., Davidson, T. J., … & Kim, S. Y. (2015). Basomedial amygdala mediates top-down control of anxiety and fear. Nature,  527(7577), 179-185. doi: 10.1038/nature15698

Lerner, T. N., Shilyansky, C., Davidson, T. J., Evans, K. E., Beier, K. T., Zalocusky, K. A., … & Deisseroth, K. (2015). Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits. Cell, 162(3), 635-647. doi: 10.1016/j.cell.2015.07.014.

Recommended Readings: Priya Rajasethupathy, M.D., Ph.D., January 25

Special Lecture
Monday, January 25, 2016
3:45 p.m., Carson Family Auditorium (CRC)

Priya Rajasethupathy, M.D., Ph.D.
Life Sciences Research Foundation Postdoctoral Fellow,
Department of Bioengineering,
Stanford University

Targeted Top-down Control of Memory Retrieval

Recommended Reading

Fiumara, F., Rajasethupathy, P., Antonov, I., Kosmidis, S., Sossin, W. S., & Kandel, E. R. (2015). MicroRNA-22 gates long-term heterosynaptic plasticity in Aplysia through presynaptic regulation of CPEB and downstream targets. Cell Reports, 11(12), 1866-1875. doi: 10.1016/j.celrep.2015.05.034.

Rajasethupathy, P., Antonov, I., Sheridan, R., Frey, S., Sander, C., Tuschl, T., & Kandel, E. R. (2012). A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell, 149(3), 693-707. doi: 10.1016/j.cell.2012.02.057.

Rajasethupathy, P., Sankaran, S., Marshel, J. H., Kim, C. K., Ferenczi, E., Lee, S. Y., … & Liston, C. (2015). Projections from neocortex mediate top-down control of memory retrieval. Nature, 526(7575), 653-659. doi: 10.1038/nature15389.

Recommended Readings: Thomas Jessell, Ph.D., December 4th

Friday Lecture Series
Friday, December 4, 2015
3:45 p.m., Caspary Auditorium

Thomas Jessell, Ph.D.
Claire Tow Professor,
Department of Neuroscience,
Department of Biochemistry and Molecular Biophysics,
Columbia University Medical Center
Investigator, Howard Hughes Medical Institute

Strategies and Circuits for Skilled Movement

Recommended Reading

Empirical Articles

Azim, E., Jiang, J., Alstermark, B., & Jessell, T. M. (2014). Skilled reaching relies on a V2a propriospinal internal copy circuit. Nature, 508(7496), 357-363. doi:10.1038/nature13021.

Fink, A. J., Croce, K. R., Huang, Z. J., Abbott, L. F., Jessell, T. M., & Azim, E. (2014). Presynaptic inhibition of spinal sensory feedback ensures smooth movement. Nature, 509(7498), 43-48. doi:10.1038/nature13276.

Mendelsohn, A. I., Simon, C. M., Abbott, L. F., Mentis, G. Z., & Jessell, T. M. (2015). Activity regulates the incidence of heteronymous sensory-motor connections. Neuron, 87(1), 111-123. doi:10.1016/j.neuron.2015.05.045.

Zampieri, N., Jessell, T. M., & Murray, A. J. (2014). Mapping sensory circuits by anterograde transsynaptic transfer of recombinant rabies virus. Neuron, 81(4), 766-778. doi:10.1016/j.neuron.2013.12.033.

Review Paper

Azim, E., Fink, A. J., & Jessell, T. M. (2014). Internal and external feedback circuits for skilled forelimb movement. Cold Spring Harbor Symposia on Quantitative Biology, 79, 81-92. doi: 10.1101/sqb.2014.79.024786.

Recommended Readings: Winrich Freiwald, Ph.D., October 30th

Friday Lecture Series
Friday, October 30, 2015
3:45 p.m., Carson Family Auditorium (CRC)

Winrich Freiwald, Ph.D.
Assistant Professor,
Laboratory of Neural Systems,
The Rockefeller University

Face to Face: New Vistas on the Neural Mechanisms of Social Cognition

Recommended Readings

Empirical Articles

Fisher, C., & Freiwald, W. A. (2015). Contrasting specializations for facial motion within the macaque face-processing system. Current Biology, 25(2), 261-266. doi:10.1016/j.cub.2014.11.038.

Meyers, E. M., Borzello, M., Freiwald, W. A., & Tsao, D. (2015). Intelligent information loss: The coding of facial identity, head pose, and non-face information in the Macaque face patch system. The Journal of Neuroscience, 35(18), 7069-7081. doi:10.1523/JNEUROSCI.3086-14.2015.

Polosecki, P., Moeller, S., Schweers, N., Romanski, L. M., Tsao, D. Y., & Freiwald, W. A. (2013). Faces in motion: selectivity of macaque and human face processing areas for dynamic stimuli. The Journal of Neuroscience, 33(29), 11768-11773. doi: 10.1523/JNEUROSCI.5402-11.2013.

Schwiedrzik, C. M., Zarco, W., Everling, S., & Freiwald, W. A. (2015). Face patch resting state networks link face processing to social cognition. PLoS Biology, 13(9), e1002245. doi:10.1371/journal.pbio.1002245

Review Papers

Brecht, M., & Freiwald, W. A. (2012). The many facets of facial interactions in mammals. Current Opinion in Neurobiology, 22(2), 259-266. doi:10.1371/journal.pbio.1002245.

Recommended Readings: Graeme Davis, Ph.D., October 2nd

Friday Lecture Series
Friday, October 2nd, 2015
3:45 p.m., Caspary Auditorium

Graeme Davis, Ph.D.
Distinguished Professor of Medicine,
Department of Biochemistry and Biophysics,
University of California San Francisco

The Stable Brain: Homeostatic Control of Neural Function

Recommended Readings

Empirical Articles

Ford, K. J., & Davis, G. W. (2014). Archaerhodopsin voltage imaging: synaptic calcium and BK channels stabilize action potential repolarization at the Drosophila neuromuscular junction. The Journal of Neuroscience, 34(44), 14517-14525. doi:10.1523/JNEUROSCI.2203-14.2014.

Gaviño, M. A., Ford, K. J., Archila, S., & Davis, G. W. (2015). Homeostatic synaptic depression is achieved through a regulated decrease in presynaptic calcium channel abundance. eLife, 4, e05473. doi:10.7554/eLife.05473.

Müller, M., Genç, Ö., & Davis, G. W. (2015). RIM-Binding protein Links synaptic homeostasis to the stabilization and replenishment of high release probability vesicles. Neuron, 85(5), 1056-1069. doi:10.1016/j.neuron.2015.01.024.

Review Papers

Davis, G. W. (2013). Homeostatic signaling and the stabilization of neural function. Neuron, 80(3), 718-728. doi:10.1016/j.neuron.2013.09.044.

Davis, G. W., & Müller, M. (2015). Homeostatic control of presynaptic neurotransmitter release. Annual Review of Physiology, 77, 251-270. doi:10.1146/annurev-physiol-021014-071740.

Recommended Readings: Erich Jarvis, Ph.D., September 28th

Special Lecture
Monday, September 28th, 2015
4:00 p.m., Carson Family Auditorium (CRC)

Erich Jarvis, Ph.D.
Associate Professor,
Department of Neurobiology,
Duke University Medical Center
Investigator, Howard Hughes Medical Institute

Dissecting the Molecular Mechanisms of Vocal Learning and Spoken Language

Recommended Readings

Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., … & Samaniego, J. A. (2014). Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 346(6215), 1320-1331. doi:10.1126/science.1253451.

Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., … & Avian Phylogenomics Consortium. (2015). Phylogenomic analyses data of the avian phylogenomics project. GigaScience, 4(1), 1-9. doi:10.1186/s13742-014-0038-1.

Pfenning, A. R., Hara, E., Whitney, O., Rivas, M. V., Wang, R., Roulhac, P. L., … & Jarvis, E. D. (2014). Convergent transcriptional specializations in the brains of humans and song-learning birds. Science, 346(6215), 1256846. doi:10.1126/science.1256846.

Whitney, O., Pfenning, A. R., Howard, J. T., Blatti, C. A., Liu, F., Ward, J. M., … & Jarvis, E. D. (2014). Core and region-enriched networks of behaviorally regulated genes and the singing genome. Science, 346(6215), 1256780. doi: 10.1126/science.1256780.

Zhang, G., Li, C., Li, Q., Li, B., Larkin, D. M., Lee, C., … & Ganapathy, G. (2014). Comparative genomics reveals insights into avian genome evolution and adaptation. Science, 346(6215), 1311-1320. doi:10.1126/science.1251385.

Recommended Readings: Jonas Frisén, M.D., Ph.D., October 16th

Friday Lecture Series
Friday, October 16, 2015
3:45 p.m., Caspary Auditorium

Jonas Frisén, M.D., Ph.D.
Tobias Foundation Professor of Stem Cell Research,
Department of Cell and Molecular Biology,
Karolinska Institutet, Stockholm, Sweden

Cellular Plasticity in the Intact and Injured Central Nervous System

Recommended Readings

Empirical Articles

Ernst, A., Alkass, K., Bernard, S., Salehpour, M., Perl, S., Tisdale, J., … & Frisén, J. (2014). Neurogenesis in the striatum of the adult human brain. Cell, 156(5), 1072-1083. doi: 10.1016/j.cell.2014.01.044

Magnusson, J. P., Göritz, C., Tatarishvili, J., Dias, D. O., Smith, E. M., Lindvall, O., … & Frisén, J. (2014). A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse. Science, 346(6206), 237-241. doi: 10.1126/science.346.6206.237.

Sabelström, H., Stenudd, M., Réu, P., Dias, D. O., Elfineh, M., Zdunek, S., … & Frisén, J. (2013). Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice. Science, 342(6158), 637-640. doi: 10.1126/science.1242576

Review Paper

Bergmann, O., Spalding, K. L., & Frisén, J. (2015). Adult neurogenesis in humans. Cold Spring Harbor Perspectives in Biology, 7(7), a018994. doi: 10.1101/cshperspect.a018994

Recommended Readings: A. James Hudspeth, M.D., Ph.D., April 27

Monday Lecture Series
Monday, April 27, 2015
4:00 p.m., Carson Family Auditorium (CRC)

A. James Hudspeth, M.D., Ph.D.
F.M. Kirby Professor and Head,
Laboratory of Sensory Neuroscience,
The Rockefeller University
Investigator, Howard Hughes Medical Institute

Making an Effort to Listen: the Active Process of the Cochlea

Recommended Readings

Empirical Articles

Fisher, J. A., Nin, F., Reichenbach, T., Uthaiah, R. C., & Hudspeth, A. J. (2012). The spatial pattern of cochlear amplification. Neuron, 76(5), 989-997. doi:10.1016/j.neuron.2012.09.031

Jacobo, A., & Hudspeth, A. J. (2014). Reaction–diffusion model of hair-bundle morphogenesis. Proceedings of the National Academy of Sciences, 111(43), 15444-15449. doi:10.1073/pnas.1417420111

Maoiléidigh, D. Ó., & Hudspeth, A. J. (2013). Effects of cochlear loading on the motility of active outer hair cells. Proceedings of the National Academy of Sciences, 110(14), 5474-5479. doi:10.1073/pnas.1302911110

Nin, F., Reichenbach, T., Fisher, J. A., & Hudspeth, A. J. (2012). Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochlea. Proceedings of the National Academy of Sciences, 109(51), 21076-21080. doi:10.1073/pnas.1219379110

Review Papers

Hudspeth, A. J. (2015). The energetic ear. Daedalus, 144(1), 42-52. doi:10.1162/DAED_a_00316

Hudspeth, A. J. (2014). Integrating the active process of hair cells with cochlear function. Nature Reviews Neuroscience, 15(9), 600-614. doi:10.1038/nrn3786

Recommended Readings: Michael W. Young, Ph.D., April 20

Monday Lecture Series
Monday, April 20, 2015
4:00 p.m., Carson Family Auditorium (CRC)

Michael W. Young, Ph.D.
Vice President for Academic Affairs,
Richard and Jeanne Fisher Professor and Head,
Laboratory of Genetics,
The Rockefeller University

Genes that Regulate Sleep and Circadian Rhythms

Recommended Readings

Empirical Articles

Levy, C., Zoltowski, B. D., Jones, A. R., Vaidya, A. T., Top, D., Widom, J., … & Leys, D. (2013). Updated structure of Drosophila cryptochrome. Nature, 495(7441), E3-E4. doi:10.1038/nature11995.

Rogulja, D., & Young, M. W. (2012). Control of sleep by cyclin A and its regulator. Science, 335(6076), 1617-1621. doi:10.1126/science.1212476.

Stavropoulos, N., & Young, M. W. (2011). insomniac and Cullin-3 regulate sleep and wakefulness in Drosophila. Neuron, 72(6), 964-976. doi:10.1016/j.neuron.2011.12.003.

Zoltowski, B. D., Vaidya, A. T., Top, D., Widom, J., Young, M. W., & Crane, B. R. (2011). Structure of full-length Drosophila cryptochrome. Nature, 480(7377), 396-399. doi:10.1038/nature10618.

Review Papers

Boothroyd, C. E., & Young, M. W. (2008). The in (put)s and out (put)s of the Drosophila circadian clock. Annals of the New York Academy of Sciences, 1129(1), 350-357. doi:10.1196/annals.1417.006

Crane, B. R., & Young, M. W. (2014). Interactive features of proteins composing eukaryotic circadian clocks. Annual Review of Biochemistry, 83, 191-219. doi:10.1146/annurev-biochem-060713-035644

Recommended Readings: Marc Tessier-Lavigne, Ph.D., April 6

Monday Lecture Series
Monday, April 6, 2015
4:00 p.m., Carson Family Auditorium (CRC)

Marc Tessier-Lavigne, Ph.D.,
President,
Carson Family Professor and Head,
Laboratory of Brain Development and Repair,
The Rockefeller University

Sculpting Neuronal Connections: The Logic and Mechanisms of Axon Growth and Pruning

Recommended Readings

Empirical Articles

Leyva-Díaz, E., del Toro, D., Menal, M. J., Cambray, S., Susín, R., Tessier-Lavigne, M., … & López-Bendito, G. (2014). FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons. Current Biology, 24(5), 494-508. doi:10.1016/j.cub.2014.01.042

Mire, E., Mezzera, C., Leyva-Díaz, E., Paternain, A. V., Squarzoni, P., Bluy, L., … & López-Bendito, G. (2012). Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nature Neuroscience, 15(8), 1134-1143. doi:10.1038/nn.3160

Romi, E., Gokhman, I., Wong, E., Antonovsky, N., Ludwig, A., Sagi, I., … & Yaron, A. (2014). ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A. Nature communications, 5. doi:10.1038/ncomms5058

Xu, K., Wu, Z., Renier, N., Antipenko, A., Tzvetkova-Robev, D., Xu, Y., … & Nikolov, D. B. (2014). Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism. Science, 344(6189), 1275-1279. doi:10.1126/science.1255149

Review Papers

Kolodkin, A. L., & Tessier-Lavigne, M. (2011). Mechanisms and molecules of neuronal wiring: a primer. Cold Spring Harbor Perspectives in Biology, 3(6), a001727. doi:10.1101/cshperspect.a001727