Recommended Readings: Wiley Prize in Biomedical Sciences

Friday Lecture Series

Wiley Prize in Biomedical Sciences

Deborah E. Wiley, chair, The Wiley Foundation, Welcome

Gunter Blobel, Ph.D., chair, Wiley Prize Jury, Award Presentation and Introduction of Award Lecture

William G. Kaelin, Jr., M.D., professor, Dana-Farber Cancer Institute and Brigham and Women’s Hospital, Harvard Medical School; investigator, Howard Hughes Medical Institute, Lessons from von Hippel-Lindau Disease

Steven McKnight, Ph.D., professor and chairman, department of biochemistry, University of Texas Southwestern Medical Center, Hitting the Bullseye of HIF2a, the Kidney Cancer Oncoprotein

Peter J. Ratcliffe, M.D., professor and head, Nuffield Department of Medicine, University of Oxford, From Epo to Oxygen: Elucidation of Hypoxia Sensing in Animals

Gregg L. Semenza, M.D., Ph.D., professor and director, vascular program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Regulation of Oxygen Homeostasis by Hypoxia-inducible Factors

April 11, 2014

3:45 p.m.-5:00 p.m. (Refreshments, 3:15 p.m., Abby Lounge)

Caspary Auditorium

Recommended Readings

Beckmann, R., Spahn, C. M. T., Eswar, N., Helmers, J., Penczek, P. A., Sali, A., . . . Blobel, G. (2001). Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell, 107(3), 361-372

Kaelin Jr., W. G., & McKnight, S. L. (2013). Influence of metabolism on epigenetics and disease. Cell, 153(1), 56-69

McKnight, S. L. (2010). On getting there from here. Science, 330(6009), 1338-1339

Ratcliffe, P. J. (2013). Oxygen sensing and hypoxia signalling pathways in animals: The implications of physiology for cancer. Journal of Physiology, 591(8), 2027-2042

Semenza, G. L. (2013). Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis. Oncogene, 32(35), 4057-4063

 

 

Recommended Readings: Talking Science, Monday, December 30

Talking Science
Caspary Auditorium
Monday, December 30, 2013
10:30 a.m.-2:30 p.m.

C. David Allis, Ph.D.
Joy and Jack Fishman Professor
Laboratory of Chromatin Biology and Epigenetics
The Rockefeller University

Epigenetics: Inheriting More Than Genes

Recommended Reading:

Epigenetics Basics

Simmons, D. (2008) Epigenetic influence and diseaseNature Education 1(1):6

In-Depth Reading

Feinberg, A. P. (2008). Epigenetics at the epicenter of modern medicine. JAMA : The Journal of the American Medical Association, 299(11), 1345–1350. doi:10.1001/jama.299.11.1345

Goldberg, A. D., Allis, C. D., & Bernstein, E. (2007). Epigenetics: a landscape takes shape. Cell, 128(4), 635–638. doi:10.1016/j.cell.2007.02.006